Founded in 1982, it doesn't think of itself as a disruptor so much as "your corner wine store, but online."

The online start-up currently offers more than 40 products, some requiring prescriptions, including erectile-dysfunction and birth-control medications.

"I wouldn't risk early capital on stuff like" brand marketing, says Bombas' David Heath. "My advice is to focus on performance marketing" first.

Via subscription, the company sells cartridges of cleaning concentrate, which people stick into squirt bottles to create nontoxic cleaning solutions.

The Fertility Awareness app provides users with answers from some 200 board-certified fertility specialists, embryologists, geneticists and even legal experts.

Nectar is a small start-up based in Montreal that develops and installs sensors for commercial beekeepers,

What will fashion rental company Le Tote do with its purchase of Lord & Taylor?

Online vintage company ThredUp's announcement that it will open small shops inside both Macy's and JC Penney is a game-changer. Will mainstream American shoppers bite, or balk?

Q&A with Patrick Robinson, a general partner at investment firm CircleUp, who's not enthused about the pure D2C model.

Despite all the hoopla over D2C brands, retail sales of clothing fell 24%, the worst month since the recession of 2008.